Best-rated hotels in Murphysboro for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Murphysboro hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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Hotels by class
4 stars 1
2 stars 2
Unrated 5
Accommodation type
Holiday homes 3
Hotels 3
Apartment 1
Motel 1
Thematic Hotels
Family Friendly hotels 4
Extended Stay 4
Vacation Rentals 4
Luxury accommodations 3
Pet-friendly hotels 2
Cheap and budget hotels 2
Hotels with indoor pool 2
Private Villas 1
Luxury hotels 1
Golf hotels 1
Central hotels 1
All Murphysboro hotels

Hotels by location

Nearby
City Center Murphysboro 4
Glenn Schlimpert Recreation Area 2
Lake Murphysboro State Park 6
General John A Logan Museum 4
Aviation Flight Murphysboro 4
Landmarks
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Parks
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Illinois >
Murphysboro

Welcome to Murphysboro

Looking to explore a charming Midwestern gem? Visit Murphysboro, where history and natural beauty collide. Immerse yourself in its rich history at local museums, embrace the picturesque scenery with hiking adventures in the Shawnee National Forest, or sample mouthwatering regional cuisine. Discover the unique blend of past and present in Murphysboro - your next unforgettable destination awaits.

What our users say about Murphysboro hotels

Warwick Allerton Chicago
9.8

Exceptional

us Ethel 07 September 2022
Fancy brand-new hotel in the middle of Chicago.
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Central Loop Hotel
9.8

Exceptional

us Ann 07 October 2022
Spotless, recently refurbished hotel, it has perfect staff and location. It is set in a central area, walking distance to a church and an art gallery.
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Eurostars Magnificent Mile
9.8

Exceptional

us Susan 14 July 2022
I liked this trendy boutique hotel and stayed for 2 nights here. I've booked king room with fantastic views and everything was perfect.
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Embassy Suites By Hilton Chicago Downtown Magnificent Mile
9.8

Exceptional

us William 14 November 2022
It was the best of Chicago hotels I visited before now. For a 4 star hotel everything was amazing, I appreciated to be here. The staff were attentive and accommodating. The location was stunning, a 10-15 minute walking distance from Chicago Water Tower.
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River Hotel
9.8

Exceptional

us Craig 13 December 2022
Enjoyed staying here. the staff were great and the location was convenient. Loads of dining options and bars nearby to grab a bite to eat or have a drink 🍹.
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Raffaello Chicago
9.8

Exceptional

us Liz 14 August 2022
The hotel was fairly clean. the location was stunning near Michigan Avenue with easy access to most shops. - I liked the updated and cozy room with a nice view. - the staff were accommodating and exceptional in every interaction we had.
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Hotel Saint Clair - Magnificent Mile
9.8

Exceptional

us Joshua 23 December 2022
The hotel is clean and budget-friendly. Located conveniently close to restaurants. The rooms are newly decorated and functional. Friendly and helpful staff at the reception desk.
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Freehand Chicago
9.8

Exceptional

us Curtis 15 February 2023
Clean rooms with air conditioning and a private bathroom, plus free WiFi 🌟.
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Hotel Felix
9.8

Exceptional

us Harry 23 August 2021
We loved this interesting place and its unbeatable location. The room we had was contemporary where toilet did n't flush. It had superb rooftop restaurant.
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Hyatt Regency Chicago
9.8

Exceptional

us Ralph 02 November 2022
I had a great time during my 2-night stay here, the location was perfect, just a short walk to Riverwalk, and the breakfast options were fantastic.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Best 4-star hotels
Quality 2-star hotels
Experience the best value for your money by checking out our selection of 4-star Murphysboro hotels.
Americas Best Value Inn

128 E Walnut Street, Murphysboro, United States

99 US$

min. price/night

Discover the hidden gems of Murphysboro by booking one of its budget-friendly hotels.
Holiday Inn Express & Suites Murphysboro - Carbondale By Ihg

120 Muddy Monster Road, Murphysboro, United States

Holiday Inn Express Murphysboro Carbondale By Ihg

120 Muddy Monster Road, Murphysboro, United States

138 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Our Murphy Home In Murphysboro Il

928 North 24Th Street, Murphysboro, United States

Excellent
4 reviews

195 US$

min. price/night

Murphysboro Retreat With Deck Near Kinkaid Lake!

495 Lakehill Rd, Murphysboro, United States

Excellent
1 review

Value Inn

128 East Walnut Street, Murphysboro, United States

75 US$

min. price/night

Fiddler On The Ridge-Woods, Wine And Wellness Villa

385 Fiddler Ridge Road, Murphysboro, United States

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